What surprised me was that this entire walk is fully hardware-driven -- no microcode involvement at all. The state machine reads the page directory entry, reads the page table entry, checks permissions, and writes back the Accessed and Dirty bits, all autonomously. Since it's hardware-driven, it runs in parallel with the microcode and needs its own memory bus arbitration -- the paging unit must share the bus with both data accesses from the microcode and prefetch requests from the instruction queue.
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This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.